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ey0019.3-8 | Congenital hypothyroidism | ESPEYB19

3.8. Transient vs permanent congenital hypothyroidism in Ontario, Canada: predictive factors and scoring system

A Marr , N Yokubynas , K Tang , D Saleh , DK Wherrett , R Stein , E Bassilious , P Chakraborty , SE Lawrence

J Clin Endocrinol Metab. 2022 Feb 17;107(3):638-648. doi: 10.1210/clinem/dgab798. PMID: 34726229Brief Summary: This large monocenter retrospective cohort study (n=469) of patients diagnosed with congenital hypothyroidism (CH) identified predictors of transient vs. permanent CH. The authors developed a 4-item risk score (0-13 points) to be used from the age of 12 months on to predict t...

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ey0017.10-8 | (1) | ESPEYB17

10.8. An anti-CD3 antibody, teplizumab, in relatives at risk for type 1 diabetes

KC Herold , BN Bundy , SA Long , JA Bluestone , LA DiMeglio , MJ Dufort , SE Gitelman , PA Gottlieb , JP Krischer , PS Linsley , JB Marks , W Moore , A Moran , H Rodriguez , WE Russell , D Schatz , JS Skyler , E Tsalikian , DK Wherrett , AG Ziegler , CJ Greenbaum , Type 1 Diabetes TrialNet Study Group

To read the full abstract: N Engl J Med. 2019 Aug 15;381(7):603613. doi: 10.1056/NEJMoa 1902226.Type 1 diabetes (T1DM) is a chronic autoimmune disease that leads to destruction of insulin producing beta cells, which leaves the patient dependent on exogenous insulin for survival. Some interventions have delayed the loss of insulin production in T1DM, but interventions to prevent clinic...

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ESPE Yearbook of Paediatric Endocrinology

3.8. Transient vs permanent congenital hypothyroidism in Ontario, Canada: predictive factors and scoring system

10.8. An anti-CD3 antibody, teplizumab, in relatives at risk for type 1 diabetes

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